Albert Einstein College of Medicine

Baker Lab Albert Einstein College of medicine, Bronx, NY

Pei Z. and Baker N.E.(2008) Competition between Delta and the Abruptex domain of Notch. BMC Dev Biol., 2008 Jan 21;8(1):4 [Abstract]

Wei Li and Nicholas Baker.(2007) The Active Role of Corpse Engulfment Pathways During Cell Competition. FLY,volume 1 | issue 5 September/October 2007 Pages: 274 - 278 [Abstract]

Tyler DM, Li W, Zhuo N, Pellock B, Baker NE.(2007) Genes affecting cell competition in Drosophila. Genetics. 2007 Feb;175(2):643-57 [Abstract]

Li, W. and Baker, N.E. (2007)  Cell competition depends on cell engulfment to induce apoptosis of neighboring cells.  Cell,2007 Jun 15;129(6):1215-25.[Abstract]

Firth, L.C., and Baker, N.E.  (2007).  Spitz from the retina regulates genes transcribed in the Second Mitotic Wave,  peripodial epithelium,  glia and plasmatocytes of the Drosophila eye imaginal disc.  Dev. Biol.,2007 Jul 15;307(2):521-38 [Abstract]

Baker, N.E.  (2007)  Patterning signals and proliferation in Drosophila imaginal discs.Curr Opin Genet Dev., 2007 Aug;17(4):287-93 [Abstract]

Tyler, D. and Baker, N.E. (2007).  expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways.  Dev. Biol., 305, 187-201.[Abstract]

Yang, L. and Baker, N.E. (2006) Notch activity opposes Ras-induced differentiation during the Second Mitotic Wave of the developing Drosophila eye. BMC Dev Biol 6, 8. [Abstract]

Firth, L.C., Li, W., Zhang, H., and Baker, N.E. (2006) Analyses of RAS regulation of eye development in Drosophila melanogaster. Meth. Enzymol.,407(56), 711-721.[Abstract]

Sidyelyeva, G., Baker, N.E. and Fricker, L.D. (2006) Characterization of the molecular basis of the drosophila mutations in carboxypeptidase D. Effect on enzyme activity and expression. J Biol Chem 281, 13844-13852. [Abstract]

Firth, L.C. and Baker, N.E. (2005) Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye. Dev Cell 8, 541-551. [Abstract]

Baker, N.E. (2004) Atonal points the way- protein-protein interactions and developmental biology. Dev Cell 7, 632-634. [Abstract]

Li, Y. and Baker, N.E. (2004) The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila. BMC Dev Biol 4, 5. [Abstract]

Shi, W., Stampas, A., Zapata, C. and Baker, N.E. (2003) The pineapple eye gene is required for survival of Drosophila imaginal disc cells. Genetics 165, 1869-1879. [Abstract]

Firth, L.C. and Baker, N.E. (2003) EGF receptor signaling: a prickly proposition. Curr Biol 13, R773-774. [Abstract]

Fu, W. and Baker, N.E. (2003) Deciphering synergistic and redundant roles of Hedgehog, Decapentaplegic and Delta that drive the wave of differentiation in Drosophila eye development. Development 130, 5229-5239. [Abstract]

Li, Y., Lei, L., Irvine, K.D. and Baker, N.E. (2003) Notch activity in neural cells triggered by a mutant allele with altered glycosylation. Development 130, 2829-2840. [Abstract]

Li, Y., Fetchko, M., Lai, Z.C. and Baker, N.E. (2003) Scabrous and Gp150 are endosomal proteins that regulate Notch activity. Development 130, 2819-2827. [Abstract]

Yang, L. and Baker, N.E. (2003) Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye. Dev Cell 4, 359-369. [Abstract]

Tyler, D. and Baker, N.E. (2003) Size isn't everything. Bioessays 25, 5-8. [Abstract]

Yu, S.Y., Yoo, S.J., Yang, L., Zapata, C., Srinivasan, A., Hay, B.A. and Baker, N.E. (2002) A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. Development 129, 3269-3278. [Abstract]

Baker, N.E. (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12, 499-507. [Abstract]

Baker, N.E. (2001) Master regulatory genes; telling them what to do. Bioessays 23, 763-766. [Abstract]

Li, Y. and Baker, N.E. (2001) Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye. Curr Biol 11, 330-338. [Abstract]

Baker, N.E. and Yu, S.Y. (2001) The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye. Cell 104, 699-708. [Abstract]

Yang, L. and Baker, N.E. (2001) Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina. Development 128, 1183-1191. [Abstract]

Lee, E.C., Yu, S.Y. and Baker, N.E. (2000) The scabrous protein can act as an extracellular antagonist of notch signaling in the Drosophila wing. Curr Biol 10, 931-934. [Abstract]

Baker, N.E. (2000) Notch signaling in the nervous system. Pieces still missing from the puzzle. Bioessays 22, 264-273. [Abstract]

Lesokhin, A.M., Yu, S.Y., Katz, J. and Baker, N.E. (1999) Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila. Dev Biol 205, 129-144. [Abstract]

Lee, E.C., Yu, S.Y., Hu, X., Mlodzik, M. and Baker, N.E. (1998) Functional analysis of the fibrinogen-related scabrous gene from Drosophila melanogaster identifies potential effector and stimulatory protein domains. Genetics 150, 663-673. [Abstract]

Baker, N.E. and Yu, S.Y. (1998) The R8-photoreceptor equivalence group in Drosophila: fate choice precedes regulated Delta transcription and is independent of Notch gene dose. Mech Dev 74, 3-14. [Abstract]

Baker, N.E. and Yu, S.Y. (1997) Proneural function of neurogenic genes in the developing Drosophila eye. Curr Biol 7, 122-132. [Abstract]

Baker, N.E., Yu, S. and Han, D. (1996) Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye. Curr Biol 6, 1290-1301. [Abstract]

Lee, E.C. and Baker, N.E. (1996) gp300sca is not a high affinity Notch ligand. Biochem Biophys Res Commun 225, 720-725. [Abstract]

Lee, E.C., Hu, X., Yu, S.Y. and Baker, N.E. (1996) The scabrous gene encodes a secreted glycoprotein dimer and regulates proneural development in Drosophila eyes. Mol Cell Biol 16, 1179-1188. [Abstract]

Hu, X., Lee, E.C. and Baker, N.E. (1995) Molecular analysis of scabrous mutant alleles from Drosophila melanogaster indicates a secreted protein with two functional domains. Genetics 141, 607-617. [Abstract]

Baker, N.E. and Zitron, A.E. (1995) Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous. Mech Dev 49, 173-189. [Abstract]